Merkel Cell
Carcinoma.
Very Rare and aggressive skin cancer of older people.
Very Rare and aggressive skin cancer of older people.
Merkel cell carcinoma (MCC) is a rare, aggressive form of skin cancer that can often spread to other areas of the body. Fortunately, if detected early, it can be treated. There is, however, a high chance that the skin cancer will return.
A total of 1.6 cases per 100,000 people are reported in Queensland. As a result of cumulative sun exposure, an older population, and more immunosuppression, MCC diagnoses are more common today than 20 years ago.
Immunosuppression, light skin tone and ultraviolet light also increase their risk.
Furthermore, there is also an association with advanced HIV, organ transplantation, or leukemia.
MCC usually presents as a rapidly growing red, blue, or purple nodule on the skin. The growths are raised, do not feel painful, and do not cause discomfort when touched.
UV-exposed areas like the face, head, and neck are common sites for them to appear, but they can develop anywhere on the body, even without exposure to sunlight!
Often seen as lumps that appear suddenly on the skin, MCC’s can be confused with pimples or sores.
Gallery of Merkel Cell Carcinoma
Please click on the images for details.
Skin cancer doctors and dermatologists rarely encounter Merkel cell carcinomas. However, MCC should be considered as a possibility in elderly individuals or immunocompromised patients with a rapidly growing nodule on their head or neck. A biopsy of the skin usually reveals the diagnosis.
Treatment for MCC requires the involvement of a range of specialists, such as a surgeon and oncologist. In most cases, surgery and radiotherapy will be required however, radiotherapy may be sufficient on its own if surgery isn’t indicated.
The bottom line
Pathologists make the diagnosis based on immunoperoxidase stains used in skin biopsies. ‘Merkel cells’, which are blue in colour, will confirm the diagnosis.
Merkel Cell – a very rare skin cancer.